Global Liver Institute

Biopsy Basics

GLOBAL LIVER INSTITUTE

Biopsy Basics

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Beyond the Biopsy Overview

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Going Beyond the Biopsy

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Resources

Liver biopsy has long been a key tool for diagnosing liver disease and remains commonly  used in clinical trials.

While biopsies have value, noninvasive diagnostics are increasingly viable in clinical practice. Noninvasive options, such as blood tests and imaging, offer several advantages: they carry no procedural risks, avoid patient discomfort, and can sometimes yield broader insights into liver health beyond the small sample obtained from a biopsy. In most cases, these noninvasive diagnostics can effectively replace the need for a liver biopsy, supporting a shift towards safer, more comprehensive diagnostic approaches.

Hepatologist Web Banner Or Landing Page. Doctor Make Liver Examination

Ask Your Doctor Before the Biopsy

  • What is the reason for doing the biopsy?
  • What are the noninvasive alternatives?
  • What are the processes for minimizing pain and discomfort?
  • How is the risk of bleeding minimized?
  • How soon will I get the results?

Complications of Biopsy

While complications from liver biopsy are rare, they can occur and include:

  • 8Bleeding
  • 8Pneumothorax (lung collapse from air leakage)
  • 8Hemothorax (blood buildup around lungs, causing chest pain)
  • 8Perforation of adjacent organs
  • 8Accidental biopsy of the kidney
  • 8Bile peritonitis (bile leakage in the abdomen, causing pain)
  • 8Infection (bacteremia, abscess, sepsis)
  • 8Hemobilia (bleeding in the bile ducts, causing pain and/or jaundice)
  • 8Death